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titles available including progressive jackpots This is a great way to increase your earning potential and keep you entertained for hours RTP Pragmatic Play is one of the leading iGaming providers and offers players a huge collection of slot games Some of these games have high RTPs which allow players to maximize their chances of winning A majority of the games offered by the company also support mobile devices which makes them perfect for use on smartphones and tablets Some of these games include bonus games that allow players to win free spins The latest release from the company Gates of Olympus takes players to the world of the ancient Greek gods in which Zeus oversees the action This highvolatility slot game comes with a Pay Anywhere feature that rewards players with wins when they hit eight or more matching symbols on the reels It also includes a lucrative Free Spins feature with multipliers that can go up to 500x the amount bet Another example of a practical trial is the Home 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to replicate reallife situations and attain maximum external validity They are usually ordered by policymakers and practitioners to help guide their decisions They can also be used to determine the causeeffect relationship of an intervention and its effects They should not however be used to replace explanatory studies The pragmatism idea is controversial and there are questions about whether pragmatic trials should replace explanatory trials or complement them Schwartz and Lellouch1 proposed a distinction between explanatory studies which support the physiological hypothesis or clinical hypothesis and pragmatic trials that inform policy and practice decisionmaking They also proposed a framework called PRECIS for pragmatic trials2 This tool attempted to define the traits of a pragmatic study which includes recruitment design implementation of the intervention and followup The number of pragmatic trials is increasing A recent Medline search using the keywords naturalistic and pragmatic which was limited to controlled trials that are randomized RCTs resulted in 34 articles which are shown in red in Figure 2 This is a sign that the health sciences community is becoming increasingly sensitized to the issue of pragmatic thinking It is important to note that the majority of these trials were conducted in primary care settings